COMPARISON OF GHRELIN HORMONE AMONG PREGNANT SUDANESE WOMEN.

Corresponding Author:
Mutasem Mahmoud Abdallah Ahmed,
Department of Clinical Chemistry,
Faculty of Medical Laboratory Sciences,
Shendi University, Sudan. Khartoum, Sudan.
E-mail: mutasemlab3@gmail.com

ABSTRACT

BACKGROUND

Multipara is basically understood to be a parity of two or higher and has stable relationship with obstetric complaints. It could be seen as a reason for unhealthy maternal and neonatal outcome.

Aims and Objectives- 1. to compare the levels of ghrelin hormone in multiparity with nulliparity and primi parity, 2. to assess the levels of ghrelin hormone in multiparity according to parity, age, gestational age, body mass index, number of miscarriages and type of delivery.

MATERIALS AND METHODS

This case control study of four hundred women aged 20-48 years from two hospitals in Khartoum state. Women were grouped into three groups comprising multiparity, primiparity and nulliparity. Questionnaires were given to the women and their blood samples were collected via vein puncture in early morning (8:00 – 11:00 am); after centrifugation of blood sample, these were analysed for ghrelin levels by using fully-automated ELISA. The sample size was taken for convenience.

RESULTS

Ghrelin levels showed significant changes in multiparity group when compared to nulliparity and also primiparity (p value<0.05). In multiparity group, ghrelin levels showed insignificant changes when classified according to age and BMI, (p value>0.05); but showed significant change when classified according to parity, type of delivery and number of miscarriage (p value<0.05).

CONCLUSION

Clinically, multiparity produces a significant variation in ghrelin level in pregnant women.

KEY WORDS

Multiparity, Primiparity, Nulliparity, Ghrelin.