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2019 Month : February Volume : 8 Issue : 7 Page : 403-406

PHOSPHOTENSIN TUMOUR SUPPRESSOR GENE (PTEN) EXPRESSION PATTERNS IN ENDOMETRIAL HYPERPLASIAS AND ENDOMETRIOID CARCINOMA.

Sithara S1, Sheela Varghese2, Sankar S3

1Resident, Department of Pathology, Government Medical College, Kottayam, Kerala, India.
2Additional Professor, Department of Pathology, Government Medical College, Kottayam, Kerala, India.
3Professor and HOD, Department of Pathology, Government Medical College, Kottayam, Kerala, India.

References :

1

Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin 2008;58(2):71-96.                       

CrossRef | Google Scholar | PubMed
2

Devi UK. Current status of gynecological cancer care in India. Journal of Gynecologic Oncology 2009;20(2):77-80.            

Google Scholar | PubMed
3

Creasman WT. Endometrial cancer: incidence, prognostic factors, diagnosis and treatment. Semin Oncol 1997;24(1 Suppl 1):S1-140, S1-50.

Google Scholar | PubMed
4

Kendall B, Ronnett B, Isacson C, et al. Reproducibility of the diagnosis of endometrial hyperplasia, atypical hyperplasia, and well-differentiated carcinoma. The American Journal of Surgical Pathology 1998;22(8):1012-9.           

CrossRef | Google Scholar | PubMed
5

Mutter GL. Diagnosis of premalignant endometrial disease. Journal of Clinical Pathology 2002;55(5):326-31.             

CrossRef | Google Scholar | PubMed
6

Tantbirojn P, Triratanachat S, Trivijitsilp P, et al. Detection of PTEN immunoreactivity in endometrial hyperplasia and adenocarcinoma. J Med Assoc Thai 2008;91(8):1161-5.             

Google Scholar | PubMed
7

Sarmadi S, Izadi-Mood N, Sotoudeh K, et al. Altered PTEN expression: a diagnostic marker for differentiating normal, hyperplastic and neoplastic endometrium. Diagnostic Pathology 2009;4(1):41.            

CrossRef | Google Scholar | PubMed
8

Balasubramaniam G, Sushama S, Rasika B, et al. Hospital-based study of endometrial cancer survival in Mumbai, India. Asian Pacific Journal of Cancer Prevention 2013;14(2):977-80.                   

CrossRef | Google Scholar | PubMed
9

Terakawa N, Kanamori Y, Yoshida S. Loss of PTEN expression followed by Akt phosphorylation is a poor prognostic factor for patients with endometrial cancer. Endocrine Related Cancer 2003;10(2):203-8.              

Google Scholar | PubMed
10

Risinger JI, Hayes AK, Berchuck A, et al. PTEN/MMAC1 mutations in endometrial cancers. Cancer Res 1997;57(21):4736-8.       

CrossRef | Google Scholar | PubMed
11

Akiyama-Abe A, Minaguchi T, Nakamura Y, et al. Loss of PTEN expression is an independent predictor of favourable survival in endometrial carcinomas. British Journal of Cancer 2013;109(6):1703-10.           

CrossRef | Google Scholar | PubMed
12

An HJ, Lee YH, Cho NH, et al. Alteration of PTEN expression in endometrial carcinoma is associated with down-regulation of cyclin-dependent kinase inhibitor, p27. Histopathology 2002;41(5):437-45.             

CrossRef | Google Scholar | PubMed
13

Mutter GL, Ince TA, Baak JP, et al. Molecular identification of latent precancers in histologically normal endometrium. Cancer Res 2001;61(11):4311-4.

CrossRef | Google Scholar | PubMed
14

Shanmugapriya M, Sudha M, Geetha P. A study of PTEN expression in endometrial hyperplasia and endometrioid type of endometrial carcinoma. Trop J Path Micro 2017;3(1):39-45.          

15

Kapucuoglu N, Aktepe F, Kaya H, et al. Immunohistochemical expression of PTEN in normal, hyperplastic and malignant endometrium and its correlation with hormone receptors, bcl-2, bax and apoptotic index. Pathology - Research and Practice 2007;203(3):153-62.                        

CrossRef | Google Scholar | PubMed
16

Orbo A, Kaino T, Arnes M, et al. Genetic derangements in the tumor suppressor gene PTEN in endometrial precancers as prognostic markers for cancer development: a population-based study from northern Norway with long-term follow-up. Gynecol Oncol 2004;95(1):82-8.            

CrossRef | Google Scholar | PubMed
17

Latta E, Chapman WB. PTEN mutations and evolving concepts in endometrial neoplasia. Curr Opin Obstet Gynecol 2002;14(1):59-65.        

CrossRef | Google Scholar | PubMed