KETAMINE AND DEXMEDETOMIDINE FOR DAY CARE ANAESTHESIA IN PAEDIATRIC SURGERY.

Corresponding Author:
Dr. Ravi Nagaprasad Yerramilli,
#B/4, Madhura Nagar,
S. R. Nagar (P.O.),
Hyderabad-500038, Telangana.
E-mail: yerramilli.rnp@gmail.com

ABSTRACT

BACKGROUND

Ketamine is one of the commonly used inducing agent for short surgical procedures particularly in paediatric patients. But, its utility has been restricted because of its unwanted sympathomimetic activity even though it has an excellent analgesic property with minimal respiratory depression. Added to this, it is also associated with undesirable postoperative delirium. In the past, several drugs like Midazolam, Propofol were added to ameliorate the side effects of Ketamine. A Combination of Dexmedetomidine, a short-acting highly selective α₂ negates the unwanted sympathomimetic effects of Ketamine. It also reduces the postoperative hallucination and its antiemetic and antisialagogues properties are beneficial. Several studies have been done to evaluate Ketamine and Dexmedetomidine as a sedative in diagnostic and invasive procedures in children. We have studied its efficacy in short surgical procedures in paediatric cases.

METHODS

The study has been done to evaluate the efficacy of dexmedetomidine-Ketamine combination in day care surgeries in paediatric patients.

RESULTS

Ketamine and Dexmedetomidine combination anaesthesia produced stable perioperative cardiovascular parameters with good postoperative sedation and smooth recovery. There were no undesirable incidences like respiratory depression or hypoventilation and PONV during postoperative period.

CONCLUSION

Ketamine-Dexmedetomidine combination provides good haemodynamic stability during intraoperative period. Dexmedetomidine has addition property of sedation, antiemesis and analgesia, which makes better choice of drug for combining with Ketamine.

KEYWORDS

Ketamine, Dexmedetomidine, Selective Alpha-2 Agonist, Day Care Surgeries.