AGRRESSIVE ANGIOMYXOMA: A RARE SOFT TISSUE TUMOR

CORRESPONDING AUTHOR:
Dr. Ritu Sharma,
Department of Pathology,
MGMCH, Jaipur.
E-mail: drritzsharma@gmail.com

ABSTRACT: Introduction-Aggerssive angiomyxoma is a rare soft tissue tumor, typically occuring in the female pelvis and carrying a high risk of local infiltration and relapse. Surgery remains the first line of treatment.¹ Material and Methods- We describe a case of perineal mass in a 20-year old woman who underwent surgical excision of the tumor. Diagnosis was made on the histopathological examination and positive immunohistochemical staining with estrogen and progesterone receptors in Pathology department of Mahatma Gandhi Medical College & Hospital, Jaipur. Discussion: Almost exclusively, AAM involves women of childbearing age; although very rare cases have been diagnosed in perimenopausal women.¹ It usually exhibit a slow, insidious growth pattern, a capacity for local infiltration and a marked tendency to repeated local recurrence. Preoperative diagnosis of AAM is often difficult because of its rarity. Misdiagnosis is common, occurring in > 80% of cases.² Histopath-ologically, differentiation may be difficult between the following: Liposarcoma, myxoma; myxoid neurofibroma.³ The methods to establish a final diagnosis is pathological analysis and immunohistochemical stain.Background: Aggressive anigomyxoma is rare mesenchymal tumor that affects women in more than 90% of cases.⁴ It is most commonly arises in the vulvovaginal region, region. Other sites in womens are perineum, pelvis, buttock and retroperitoneum.¹ The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with local recurrence.⁵